대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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- Pages.96-97
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- 2002
In Vivo Roles of Lysophospholipid Receptors Revealed by Gene Targeting Studies in Mice
- Ishii, Isao (Department of Molecular Genetics, National Institute of Neuroscience, National Center of Neurology and Psychiatry (NCNP))
- 발행 : 2002.10.01
초록
Lysophosphatidic acid (LPA) and sphingosine 1-phosphate (SIP) are bioactive lysophospholipids (LPs) that act as mediators in various cellular processes, such as cell growth, differentiation, survival, motility, and cytoskeletal reorganization (1,2). LPA and S1P are both abundant in serum and are produced by activated platelets and other cell types. (omitted)
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