Proceedings of the KSAR Conference (한국동물번식학회:학술대회논문집)
- 2002.06a
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- Pages.95-95
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- 2002
Enhancement of Growth Performance in Transgenic Rabbits with Overexpressing Growth Hormone Receptor and IGF-1 Receptor Genes
- Chang, Suk-Min (Devision of Applied Biological Science, Sun Moon University) ;
- Kim, Hyun-Ju (Devision of Applied Biological Science, Sun Moon University) ;
- Kim, Jin-Young (Department of Animal Science and Technology, Seoul National University) ;
- Park, Wha-Sik (Department of Clinical Pathology, Kim Cheon University) ;
- Im, Kyung-Soon (Department of Animal Science and Technology, Seoul National University) ;
- Dong IL Jin (Devision of Applied Biological Science, Sun Moon University)
- Published : 2002.06.01
Abstract
Transgenic rabbits were produced by micoinjection of DNA containing metallothionein promoter ligated to growth hormone receptor (GHR) and IGF-l receptor (IGF-lR) genes. Founder transgenic rabbits transmitted transgenes into pups with Medelian ratio. The mRNA expression of transgenes using Northern blotting with probes of IGF-IR and GHR genes was checked in liver of transgenic rabbits. Transgenic rabbits with IGF-IR and GHR genes more expressed mRNA than control non-transgneic rabbits. (omitted)