URINARY PAH METABOLITES INFLUENCED BY GENETIC POLYMORPHISMS OF GSTM1 IN HOSPITAL INCINERATING WORKERS

  • Lee, Kyoung-Ho (Department of Preventive Medicine, Seoul National University College of Medicine) ;
  • Cho, Soo-Hun (Department of Preventive Medicine, Seoul National University College of Medicine) ;
  • Park, Inmi (Institute for Environmental Medicine, Medical Research Center, Seoul National University) ;
  • Deahee Kang (Department of Preventive Medicine, Seoul National University College of Medicine)
  • Published : 2002.11.01

Abstract

Hospital waste incinerating workers are exposed to various pyrolysis products including polycyclic aromatic hydrocarbons (PARs). We evaluated their exposure by assessing urinary 1-hydroxypyrene glucuronide (1-OHPG), as internal dose of PAH exposure. The potential effect of genetic polymorphisms of GSTM1/T1 involved in PAH metabolisms was also investigated.(omitted)

Keywords