Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)

Korean Society of Toxicology & Korea Environmental Mutagen Society (한국독성학회)
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INVOLVEMENT OF THE MODULATED-NEURONAL NITRIC OXIDE SYNTHASE ACTIVITIES THROUGH INTERACTIONS OF PROTEIN KINASES IN LEAD NEUROTOXICITY

  • Park, Ji-Young (Department of Pharmacology, Medicinal of Medicine, Inha University) ;
  • Kang, Ju-Hee (Department of Pharmacology, National Institute of Toxicology Research, KFDA) ;
  • Chung, Woon-Gye (Department of Pharmacology, Medicinal of Medicine, Inha University) ;
  • Park, Chang-Shin (Department of Pharmacology, Medicinal of Medicine, Inha University)
  • Published : 2002.11.01
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Abstract

This work aimed to identify neuronal cell toxicity induced by decrease of physiological NO production by differential phosphorylation of constitutive neuronal NO synthase (nNOS), which can be mediated by Ca2+-dependent PKC and/or CaM-KII activities activated by metals.(omitted)

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