Activation of toll-like receptor signaling by polysaccharide isolated from cell culture of Acantopanax senticosus

  • Ahn, H-J (Biopotency Evaluation Laboratory, Korea Research Institute of Bioscience Biotechnology (KRIBB)) ;
  • Han, S-B (Biopotency Evaluation Laboratory, Korea Research Institute of Bioscience Biotechnology (KRIBB)) ;
  • Yoon, Y-D (Biopotency Evaluation Laboratory, Korea Research Institute of Bioscience Biotechnology (KRIBB)) ;
  • Lee, H-S (Biopotency Evaluation Laboratory, Korea Research Institute of Bioscience Biotechnology (KRIBB)) ;
  • Moon, J-S (Biopotency Evaluation Laboratory, Korea Research Institute of Bioscience Biotechnology (KRIBB)) ;
  • Lee, C-W (Biopotency Evaluation Laboratory, Korea Research Institute of Bioscience Biotechnology (KRIBB)) ;
  • Lee, K-H (Biopotency Evaluation Laboratory, Korea Research Institute of Bioscience Biotechnology (KRIBB)) ;
  • Park, S-K (Biopotency Evaluation Laboratory, Korea Research Institute of Bioscience Biotechnology (KRIBB)) ;
  • Kim, H-C (Biopotency Evaluation Laboratory, Korea Research Institute of Bioscience Biotechnology (KRIBB))
  • Published : 2002.11.01

Abstract

We investigated the mechanism of immunomodulatory action of polysaccharide isolated from cell culture of Acanthopanax senticosus (ASP). ASP was found to increase directly proliferation and differentiation of B cells, and cytokine production of macrophages, but not proliferation and cytokine production of T cells.(omitted)

Keywords