한국독성학회:학술대회논문집 (Proceedings of the Korean Society of Toxicology Conference)
- 한국독성학회 2002년도 Molecular and Cellular Response to Toxic Substances
- /
- Pages.146-146
- /
- 2002
IN VITRO AND IN VIVO EVALUATION OF THE GENOTOXIC EFFECT OF 2-BROMOPROPANE BY THE ALKALINE SINGLE-CELL GEL ELECTROPHORESIS(COMET) ASSAY
- Kim, Soo-Jin (Center for Occupational Toxicology, Occupational Safety and Health Research Institute, Korea Occupational Safety ＆ Health Agency) ;
- Yu, Il-Je (Center for Occupational Toxicology, Occupational Safety and Health Research Institute, Korea Occupational Safety ＆ Health Agency) ;
- Lee, Yong-Mook (Center for Occupational Toxicology, Occupational Safety and Health Research Institute, Korea Occupational Safety ＆ Health Agency) ;
- Chung, Ho-Keun (Center for Occupational Toxicology, Occupational Safety and Health Research Institute, Korea Occupational Safety ＆ Health Agency) ;
- Maeng, Seung-Hee (Center for Occupational Toxicology, Occupational Safety and Health Research Institute, Korea Occupational Safety ＆ Health Agency)
- 발행 : 2002.11.01
초록
The alkaline single cell gel electrophoresis (comet) assay was used to clarify in vitro and in vivo genotoxicity of 2-bromopropane (2-BP). For in vitro studies, fresh medium containing 2-BP (2.50, 1.00, 0.50, 0.25, 0.10, 0.05, 0.01 mM, and vehicle control) were added in human lymphocytes.(omitted)