TGF-$\beta$ INDUCES INVASIVE PHENOTYPE OF MCF10A HUMAN BREAST EPITHELIAL CELLS

  • Kim, Mi-Sung (College of Pharmacy, Duksung Women′s University) ;
  • Aree Moon (College of Pharmacy, Duksung Women′s University)
  • 발행 : 2002.11.01

초록

Transforming growth factor-${\beta}$ (TGF-${\beta}$), a hormonally active polypeptide found in normal and transformed tissues, regulates cellular growth and phenotyphic plasticity. We have previously shown that H-ras, but not N-ras, induces invasive phenotype in MCF10A human breast epithelial cells.(omitted)

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