Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2002.11b
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- Pages.140-140
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- 2002
ROLES OF MAPK PATHWAYS IN GDNF-INDUCED GLIOMA CELL MIGRATION
- Hyun Song (College of Pharmacy, Duksung Women′s University) ;
- Chung, Dong-June (Sungkyunkwan University) ;
- Choung, Pill-Hoon (Seoul National University) ;
- Aree Moon (College of Pharmacy, Duksung Women′s University)
- Published : 2002.11.01
Abstract
Glial cell-derived neurotrophic factor (GDNF) is a potent neurotrophic factor that enhances survival of midbrain doparminergic neuron and is a member of the transforming growth factor-b superfamily. GDNF and its receptors are widely distributed in brain and are believed to be involved in the control of neuron survival, proliferation and differentiation.(omitted)