Toxicogenomics approaches in Toxicological Pathology

  • Shirai, Tomoyuki (Nagoya City University Graduate of Medical Sciences, Nagoya Japan)
  • Published : 2002.11.01

Abstract

It is believed that cell and/or tissue toxicity is resulted from alterations in expression of many genes in response to environmental stresses or toxicants. New technology, such as DNA microarray analysis, can measure the expression of thousands of genes at a time providing the potential to accelerate discovery of toxicant pathways and specific gene targets.(omitted)

Keywords