SAFETY EVALUATION OF SUNSCREENS (I) ; CORRELATION BETWEEN SUN PROTECTION FACTOR AND SKIN IRRITATION

  • Suh, Soo-Kyung (Division of Safety Evaluation, National Institute of Toxicological Research) ;
  • Kim, Jong-Won (Division of Safety Evaluation, National Institute of Toxicological Research) ;
  • Park, Ju-Young (Division of Safety Evaluation, National Institute of Toxicological Research) ;
  • Seo, Kyung-Won (Division of Safety Evaluation, National Institute of Toxicological Research) ;
  • Park, Chang-Won (Division of Safety Evaluation, National Institute of Toxicological Research) ;
  • Kim, Kyu-Bong (Division of Safety Evaluation, National Institute of Toxicological Research) ;
  • Kim, Kwang-Jin (Division of Safety Evaluation, National Institute of Toxicological Research) ;
  • Kim, Jong-Min (Division of Safety Evaluation, National Institute of Toxicological Research) ;
  • Lee, Sun-Hee (Division of Safety Evaluation, National Institute of Toxicological Research)
  • Published : 2002.05.01

Abstract

In recent years, the safety of sunscreens has been challenged based on the reports of its adverse effect on users; dermatitis, allergic contact dermatitis, photoallergic contact dermatitis. To investigate a correlation between sun protection factor (SPF) and the safety of sunscreens, we measured in vitro SPF index using homosalate as a standard and examined the toxicity tests on cosmetics; primary and cumulative skin irritation tests, ocular irritation test, and skin sensitization test.(omitted)

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