한국독성학회:학술대회논문집 (Proceedings of the Korean Society of Toxicology Conference)
- 한국독성학회 2002년도 Current Trends in Toxicological Sciences
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- Pages.137-137
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- 2002
BIOLOGICALLY BASED DOSE-RESPONSE (BBDR) MODELING USING BIOMARKERS FOR CANCEER RISK ASSESSMENT
- Song, Hyun-Sue (SungKyunKwan University) ;
- Lee, Byung-Mu (SungKyunKwan University)
- 발행 : 2002.05.01
초록
Biologically Based Dose-Response (BBDR) models were developed using biomarkers for cancer risk assessment. To establish the relationship among biomarkers, exposure dose and tumor response, biomarkers in the lung, liver, stomach or blood were measured after a single or continuous administration of selected carcinogen (; BaP) in mice or rats.(omitted)