THE MICROSOMAL EPOXIDE HYDROLASE(MEPHXS) POLYMORPHISMS AND THE ASSOCIATION OF MICRONUCLEI(MN) IN THE BENZENE-EXPOSED WORKERS

  • Kim, Tae-Yon (School of Public Health, Seoul National University) ;
  • Kwon, Seul-A (School of Public Health, Seoul National University) ;
  • Kim, Jin-Sik (School of Public Health, Seoul National University) ;
  • Kim, Su-Young (School of Public Health, Seoul National University) ;
  • Lee, Young-Jun (School of Public Health, Seoul National University) ;
  • Chung, Eun-Jung (School of Public Health, Seoul National University) ;
  • Paek, Do-Myung (School of Public Health, Seoul National University) ;
  • Park, Jung-Keun (School of Public Health, Seoul National University) ;
  • Chung, Hai-Won (School of Public Health, Seoul National University)
  • Published : 2002.05.01

Abstract

In order to investigate whether genetic polymorphisms in the mEH exon3 (Tyr139His), exon4 (His113Arg) interact with the formation of MN in benzene exposed workers, the PCR-RFLP based genotyping of 76 exposed and 115 controls were performed and cytokinesis-block micronucleus (CBMN) analysis of 56 exposed and 53 controls was employed.(omitted)

Keywords