한국독성학회:학술대회논문집 (Proceedings of the Korean Society of Toxicology Conference)

한국독성학회 (Korean Society of Toxicology & Korea Environmental Mutagen Society)
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PRESENILIN-2 MUTATION ALTERS NEURITE EXTENTION, APOPTOSIS AND TRANSCRIPTION FACTOR(NF-KB) ACTIVATION

  • 발행 : 2002.05.01
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초록

Alzheimer's disease (AD) is characterized by $\beta$-amyloid deposition and associated with loss of neuron cells in brain regions involved in learning and memory process. Many cases of early onset autosomal dominant inherited forms of AD are caused by mutation in the genes encoding presenilin-2 (PS-2).(omitted)

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