REQUIREMENT OF METABOLIC ACTIVATION OF PUERARIA MIRIFICA FOR ESTROGENIC ACTIVITY

  • Yang, Se-Ran (Laboratory of stem cell and tumor biology, Department of Veterinary Public Health, College of Veterinary Medicine, Seoul National University) ;
  • Cho, Sung-Dae (Laboratory of stem cell and tumor biology, Department of Veterinary Public Health, College of Veterinary Medicine, Seoul National University) ;
  • Park, Ki-Soo (Laboratory of stem cell and tumor biology, Department of Veterinary Public Health, College of Veterinary Medicine, Seoul National University) ;
  • Hong, In-Sun (Laboratory of stem cell and tumor biology, Department of Veterinary Public Health, College of Veterinary Medicine, Seoul National University) ;
  • Jo, Eun-Hye (Laboratory of stem cell and tumor biology, Department of Veterinary Public Health, College of Veterinary Medicine, Seoul National University) ;
  • Seo, Min-Soo (Laboratory of stem cell and tumor biology, Department of Veterinary Public Health, College of Veterinary Medicine, Seoul National University) ;
  • Lee, Yong-Soon (Laboratory of stem cell and tumor biology, Department of Veterinary Public Health, College of Veterinary Medicine, Seoul National University) ;
  • Kang, Kyung-Sun (Laboratory of stem cell and tumor biology, Department of Veterinary Public Health, College of Veterinary Medicine, Seoul National University)
  • Published : 2002.05.01

Abstract

A wide range of chemicals derived from plant and human-made xenobiotics are reported to have hormonal activity. The present studies were performed to examine the estrogenic effect of Kwao Keur, Pueraria mirifica (PM), that has been used a rejuvenating folk medicine from Thailand, using recombinant yeast, MCF-7 cell proliferation and HepG2 cell transient transfection assay.(omitted)

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