Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2002.05a
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- Pages.93-93
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- 2002
GENERATION OF FREE RADICALS BY INTERACTION OF IRON WITH THIOLS IN HUMAN PLASMA
- Lee, Seung-Jin (College of Pharmacy, Seoul National University) ;
- Chung, Ka-Young (College of Pharmacy, Seoul National University) ;
- Chung, Jin-Ho (College of Pharmacy, Seoul National University)
- Published : 2002.05.01
Abstract
Oxidative stress has been associated with a number of diseases in humans. Among the sources that can generate oxidative stress, it has been reported that iron can generate reactive oxygen species (ROS) with thiol. In iron overload state, increased thiol levels in plasma appeared to be associated with human mortality.(omitted)