Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2002.05a
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- Pages.91-91
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- 2002
ALL TRANS RETINOIC ACID AND 9-cis RETINOIC ACID INHIBIT CELL PROLIFERATION ON HUMAN BREAST CANCER CELL UNE MCF-7
- Yoon, Hyun-Jung (College of Medicine HanYang University) ;
- Gu Kong (College of Medicine HanYang University) ;
- Sheen, Yhun-Yhong (College of Pharmacy Ewha Womens University)
- Published : 2002.05.01
Abstract
We have examine the effect of all trans retinoic acid and 9-cis-retinoic acid on human breast cancer cell proliferation using SRB assay and cell cycle analysis. 1)In MCF-7 cells, in the presence of phenol red, either all trans retinoic acid or 9-cis-retinoic acid treatment showed the inhibition of the cell proliferation over control cells and also inhibit the estrogen stimulated cell proliferation when it was given together with estrogen.(omitted)