Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2002.05a
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- Pages.89-89
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- 2002
OXIDANT-INDUCED NEUROTOXICITY WAS BLOCKED BY ANTIOXIDANTS AND METAL CHELATORS IN MOUSE CEREBRAL NEURON CULTURES
- Park, S.T. (Department of Anatomy, School of Medicine, Wonkwang University) ;
- H.Y. Yoon (Department of Pediatrics, School of Medicine, Wonkwang University)
- Published : 2002.05.01
Abstract
It is well known that oxygen radicals induce neuronal cell damage by initiation of lipid peroxidation chain reaction. Recent work has been also demonstrated that enzymatically generated free radicals cause the release of glutamate and aspartate from cultured rat hippocampal slices.(omitted)