RADIATION SENSITIVITY DEPENDS ON OGG1 ACTIVITY STATUS IN HUMAN LEUKEMIA CELL LINES

  • 발행 : 2002.05.01

초록

To assess the role of 8-oxoguanine glycosylase (OGG1) in the cell defense against radiation injury, the radiation-induced cytotoxicities were compared between the mutant type KG-1 featuring a loss of OGG1 activity due to a homozygous mutation of Arg 229 G1n, and the wild type U937.(omitted)

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