한국생물공학회:학술대회논문집
- 한국생물공학회 2001년도 추계학술발표대회
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- Pages.886-889
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- 2001
Molecular analysis of c-terminus structure for elucidating the stabilization effect of site-specific immobilization
- 발행 : 2001.11.07
초록
C-terminus specific immobilization often results in a increased structural stability resistant to various denaturation factors. In order to elucidate the immobilization effect on the c-terminus in molecular level, we made over 200 protein data set from Protein Data Bank(PDB), analyzed c-terminus structure of each protein, and investigated the structural relationship with the stabilizing factors such as hydrogen bond, ion pairs, cation pi, disulfide bond, solvation free energy, surface area, flexibility and so on.
키워드