약모밀(Houttuynia cordata) 뿌리에서 추출한 순차분획물의 항균활성

Antimicrobial activities, extraction yields and chemical compositions of the extracts from the powder of vacuum dried Houttuynia cordata root on various solvents were investigated. Antimicrobial activity was investigated by disc diffusion method against several microorganisms, nine species of Gram positive and thirteen Gram negative bacteria. Ethanol, ethylacetate and butanol extracts exhibited potent antimicrobial activities against B. megaterium C. xerosis, S. aureus, S. epidermidis and E.coli. Chloroform and aqueous extracts from H. cordata showed weak antimicrobial activity against the tested bacteria. Ethylacetate and butanol extracts exhibited strong antimicrobial activity against the tested microorganisms. The extraction yields were 15.7%, 3.7%, 0.13%, 0.5% and 5.9% in ethanol, chloroform, ethylacetate, butanol and aqueous fractions, respectively. To further elucidate the effective components, solvent extracts was analyzed by GC/MSD.

약모밀(Houttuynia cordata)의 뿌리에서 추출한 ethanol, chloroform, ethylacetate, butanol 및 수용성 추출물의 항균활성을 9 종의 Gram 양성균과 13 종의 Gram 음성균에 대하여 disc diffusion 방법으로 조사하였다. Ethanol, ethylacetae, butanol 추출물은 B. megaterium C. xerosis, S. aureus, S. epidermidis 및 E.coli 에 대하여 항균활성을 나타내었고, chloroform과 수용성 추출물은 활성이 나타나지 않거나 미약하였다. 그러나 Ethylacetate와 butanol 추출물은 상대적으로 낮은 농도에서 강한 항균활성을 나타내었다.