대한전기학회:학술대회논문집 (Proceedings of the KIEE Conference)
- 대한전기학회 2001년도 추계학술대회 논문집 전기물성,응용부문
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- Pages.274-276
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- 2001
집적형 DNA칩 미소 전극 어레이 및 비수식화 표적 DNA를 이용한 유전자 검출
Genome Detection Using an Integrated type DNA Chip Microelectrode-array and Non-labeling Target DNA
- 최용성 (대판대학교 산업과학연구소) ;
- 이혜연 (대판대학교 산업과학연구소) ;
- 전중유행 (대판대학교 산업과학연구소) ;
- 전중수화 (대판대학교 산업과학연구소) ;
-
권영수
(동아대학교 전기전자컴퓨터공학부)
;
- 천합지이 (대판대학교 산업과학연구소)
- Choi, Yong-Sung (The Institute of Scientific and Industrial Research, Osaka University) ;
- Lee, Hea-Yeon (The Institute of Scientific and Industrial Research, Osaka University) ;
- Tanaka, Hiroyuki (The Institute of Scientific and Industrial Research, Osaka University) ;
- Tanaka, Hidekafu (The Institute of Scientific and Industrial Research, Osaka University) ;
-
Kwon, Young-Soo
(Division of Electrical, Electronics and Computer Eng., Dong-A University)
;
- Kawai, Tomoii (The Institute of Scientific and Industrial Research, Osaka University)
- 발행 : 2001.11.03
초록
This research aims to develop the multiple channel electrochemical DNA chip using microfabrication technology. At first, we fabricated a high integration type DNA chip array by lithography technology. Several probe DNAs consisting of thiol group at their 5-end were immobilized on the sold electrodes. Then target DNAs were hybridized and reacted. Cyclic voltammetry showed a difference between target DNA and control DNA in the anodic peak current values. Therefore, it is able to detect a plural genes electrochemically after immobilization of a plural probe DNA and hybridization of non-labeling target DNA on the electrodes simultaneously. It suggested that this DNA chip could recognize the sequence specific genes.
키워드