Proceedings of the Korean Biophysical Society Conference (한국생물물리학회:학술대회논문집)

The Korean Biophysical Society (한국생물물리학회)
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D-Erythroascorbic acid regulates cyanide-resistant respiration in Candida albicans

  • Lee, Jung-Shin (Laboratory of Biophysics, School of Biological Sciences and Institute of Microbiology, Seoul National University) ;
  • Huh, Won-Ki (Laboratory of Biophysics, School of Biological Sciences and Institute of Microbiology, Seoul National University) ;
  • Kang, Sa-Ouk (Laboratory of Biophysics, School of Biological Sciences and Institute of Microbiology, Seoul National University)
  • Published : 2001.06.01
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Abstract

Candida albicans possess cyanide-resistant respiratory pathway, which is mediated by alternative oxidase. The activity of alternative oxidase has been found to be dependent on several regulatory mechanisms. In order to investigate the influence of D-erythroascorbic acid on respiration of C. albicans, the respiratory activity of the cells was measured with oxygen monitor. ALO1 is known to encode D-arabinono-1,4-lactone oxidase that catalyses the final step of D-erythroascorbic acid biosynthesis in C. albicans.(omitted)

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