Proceedings of the Korean Biophysical Society Conference (한국생물물리학회:학술대회논문집)
- 2001.06a
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- Pages.23-23
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- 2001
Synaptic Facilitation of Naive and Depressed Synapses in Aplysia
- Chang, Deok-Jin (School of Biological Sciences, College of Natural Sciences, Seoul National University) ;
- Kaang, Bong-Kiun (School of Biological Sciences, College of Natural Sciences, Seoul National University)
- Published : 2001.06.01
Abstract
To evaluate the contribution of cAMP/PKA signal pathway in short-term facilitation, we overexpressed Ap oal receptor in sensory neurons that do not normally express this receptor. We have previously shown that activation of this receptor in sensory cells, by a brief treatment with octopamine (OA), produced short-term facilitation such as membrane depolarization, increase in membrane excitability, spike broadening, and enhanced neurotransmitter release in non-depressed synapse.(omitted)
Keywords