Mechanotransduction in Cardiac Myocytes

  • Earm, Yung-E (National Research Laboratory for Cellular Signalling and Department of Physiology & Biophysics, Seoul National University College of Medicine)
  • Published : 2001.06.01

Abstract

It is well known that myocardial stretch causes changes in electrical signalling and contractility of the heart. For example, mechanical stretch depolarises the membrane potential of cardiac cells and alters the shape of action potentials. As a result, these effects either accelerate the frequency of heart rate or induce arrhythmias of the heart.(omitted)

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