Proceedings of the KSAR Conference (한국동물번식학회:학술대회논문집)
- 2001.10a
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- Pages.53-54
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- 2001
Expression of the Novel Basic Helix-Loop-Helix Gene dHAND in Neural Crest Derivatives and Extraembryonic Membranes during Mouse Development
- S.I Yun (Genetic Resources Center, Korea Research Institute of Bioscience ＆ Biotechnology) ;
- Kim, S.K (Department of genetic Engineering, Sungkyunkwan Universit) ;
- Kim, S.K. (Genetic Resources Center, Korea Research Institute of Bioscience ＆ Biotechnolog) ;
- K.T Chang (Genetic Resources Center, Korea Research Institute of Bioscience ＆ Biotechnolog) ;
- B.H Hyun (Genetic Resources Center, Korea Research Institute of Bioscience ＆ Biotechnolog) ;
- D.S Son (National Livestock Research Institut) ;
- Kim, M.K (Chungnam, College of Veterinary Medicine, Chungnam National Universit) ;
- D.S Suh (Department of genetic Engineering, Sungkyunkwan University)
- Published : 2001.10.01
Abstract
Expression of HAND genes in sympathetic adrenal lineage suggests that HAND genes may regulate Mash-I independent neuronal genes. HAND genes are also expressed in other cell types, e.g. Cardiac cells, trophoblasts, and decidua, suggesting that HAND genes are not cell fate determination factors. It is unclear how HAND genes function specifically in different types of cells. Combinational actions of HANDs with other cell-lineage specific transcription factor may determine each cell fate and differentiation processes. Identifying the transcription target genes of HANDs and Mash-I will be important to elucidate the function of these bHLH factors in SNS factors in SNS development. (omitted)
Keywords