Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2001.10a
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- Pages.185-185
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- 2001
ACTIVATION OF CD95 RECEPTOR MODULATES CYP3A4 EXPRESSION THROUGH CERAMIDE AND NITRIC OXIDE PRODUCTION IN HUMAN COLON CARCINOMA HT-29 CELLS
- Yang, Soon-Ae (College of Pharmacy, Chungang University) ;
- Lee, Sang-Kwang (College of Pharmacy, Chungang University) ;
- Park, Sung-Sik (College of Pharmacy, Chungang University) ;
- Kim, Mie-Young (College of Pharmacy, Chungang University) ;
- Chun, Young-Jin (College of Pharmacy, Chungang University)
- Published : 2001.10.01
Abstract
The CD95 (Fas, APO-1) is known to play a key role as a transmembrane cell surface receptor that mediates apoptosis of many cell types through binding with Fas ligand or cross-linking to agonistic anti-Fas antibody. Activation of CD95 provokes a potent and rapid responses in a variety of cell types by unknown mechanism.(omitted)
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