Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2001.10a
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- Pages.180-180
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- 2001
MUTAGENICITY TESTS OF A NEW CEPHALOSPORIN ANTIBIOTIC AGENT, IDC-7181
- Zheng, Mei-Shu (College of Veterinary Medicine, Chungbuk National University) ;
- Sin, Ji-Soon (College of Veterinary Medicine, Chungbuk National University) ;
- Kwon, Young-Bang (College of Veterinary Medicine, Chungbuk National University) ;
- Nam, Sang-Yoon (College of Veterinary Medicine, Chungbuk National University) ;
- Kang, Jong-Koo (College of Veterinary Medicine, Chungbuk National University)
- Published : 2001.10.01
Abstract
The mutagenic potency of a new antibiotics, IDC- 7181, was evaluated using the mutagenicity tests including Ames, chromosome aberration and micronucleus tests. In bacterial reversion assay, IDC-7181 did not show any mutagenic response in the absence or presence of S9 mixture with Salmonella typhimurium TA98, TAlOO, TA1535 and TA1537 and E. coli WP2uvrA-(100, 50, 25, 12.5 and 6.25
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