MODULATION OF CELL CYCLE-RELATED PROTEIN EXPRESSION BY RESVERATROL IN HUMAN LUNG CANCER CELLS

  • Kim, Young-Ae (Department of Biochemistry, College of Oriental Medicine, Dong-Eui University) ;
  • Kong, Kyu-Ri (Department of Biochemistry, College of Oriental Medicine, Dong-Eui University) ;
  • Lee, Won-Ho (Department of Biology, Pusan National University) ;
  • Park, Kun-Young (Department of Food Science and Nutritio) ;
  • Rhee, Suk-Hee (Department of Food Science and Nutritio) ;
  • Park, Yung-Hyun (Department of Biochemistry, College of Oriental Medicine, Dong-Eui University)
  • Published : 2001.10.01

Abstract

Resveratrol (3,5,4'-trihydroxy-trans-stilbene), a phytoalexin found in grapes and wines is a potent antioxidant with cancer-preventive properties, the mechanism by which resveratrol imparts cancer chemopreventive effect is poorly defined. The aim of the present study was to further elucidate the possible mechanisms by which resveratrol exerts its anti-proliferative action in cultured human lung cancer cells.(omitted)

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