Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2001.10a
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- Pages.139-140
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- 2001
IH-901, AN INTESTINAL BACTERIAL METABOLITE DERIVED FROM THE PROTOPANAXADIOL GINSENOSIDE, HAS ANTI-TUMOR PROMOTING EFFECTS IN MOUSE SKIN.
- Lee, Ji-Yoon (College of Pharmacy, Seoul National University) ;
- Chun, Kyung-Soo (College of Pharmacy, Seoul National University) ;
- Sung, Jong-Hwan (Ilhwa Co. Ltd) ;
- Surh, Young-Joon (College of Pharmacy, Seoul National University)
- Published : 2001.10.01
Abstract
Ginseng saponins (ginsenosides) have been regarded as principal components responsible for the majority of pharmacological activities exerted by ginseng. IH-901, an intestinal bacterial metabolite derived from the protopanaxadiol saponin of Panax ginseng C.A. Meyer, has been reported to have anti-tumor effects including inhibition of angiogenesis, invasion and metastasis, as well as induction of tumor cell apoptosis. (omitted)
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