EFFECT OF CAPSAICIN ON LPS-INDUCED PROSTAGLANDIN E2 PRODUCTION BY MURINE PERITONEAL MACROPHAGES

  • 발행 : 2001.10.01

초록

Proinflamamtory mediators such as prostaglandins (PGs), cyclooxygenase-2 (COX-2), and inducible nitric oxide synthase (iNOS) are known to be key mediators in pathogenesis of inflammatory diseases. Capsaicin, the major ingredient of hot pepper, is considered to elicit anti-inflammatory property. In this study, the effect of capsaicin on the prostaglandin E$_2$(PGE$_2$) production was investigated in murine peritoneal macrophages.(omitted)

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