Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2001.10a
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- Pages.128-129
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- 2001
TILIANIN PREVENTS DIET-INDUCED ATHEROSCLEROSIS BY INHIBITION OF NUCLEAR FACTOR $\textsc{k}$ B (NF- $\textsc{k}$ B) ACTIVATION IN LDL RECEPTOR DEFICIENT MICE
- Nam, Kung-woo (Genetic Resources Center, Korea Research Institute of Bioscience and Biotechnology) ;
- Woonchon Mar (Natural Products Research Institute, Seoul National University) ;
- Cho, Myung-Hang (Laboratory of Toxicology College of Veterinary Medicine, Seoul National University) ;
- Hong, Jung-Joo (Genetic Resources Center, Korea Research Institute of Bioscience and Biotechnolog) ;
- Park, Jae-Hoon (Genetic Resources Center, Korea Research Institute of Bioscience and Biotechnolog) ;
- Oh, Goo-Tag (Genetic Resources Center, Korea Research Institute of Bioscience and Biotechnology)
- Published : 2001.10.01
Abstract
Tilianin, purified from acrial part of Agastache rugosa Kuntze, reduces progression and may induce some regression of aortic foam cell formation in low density lipoprotein receptor deficient mice (LDLR -/- mice). We investigated whether tilianin can prevent high fat diet-induced atherosclerosis. Twenty-six male mice were divided into three groups.(omitted)
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