Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2001.10a
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- Pages.115-115
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- 2001
BETA-AMYLOID INDUCES OXIDATIVE AND/OR NITRATIVE PC12 CELL DEATH VIA PRO-INFLAMMATORY MECHANISMS
- Jang, Jung-Hee (College of Pharmacy, Seoul National University) ;
- Surh, Young-Joan (College of Pharmacy, Seoul National University)
- Published : 2001.10.01
Abstract
Oxidative stress induced by reactive oxygen and/or nitrogen species has been considered as a major cause of cellular injuries in a variety of neurodegenerative disorders including Alzheimers disease (AD). Inflammatory as well as oxidative tissue damage has been associated with pathophysiology of AD, and non-steroidal anti-inflammatory drugs have been reported to have beneficial effects in the treatment or prevention of AD.(omitted)
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