ANTICLASTOGENIC, ANTIGENOTOXIC AND APOPTOTIC ACTIVITY OF NATURAL POLYPHENOLS

  • Chakraborty, S. (Department of Environmental Carcinogenesis and Toxicology Chittaranjan National Cancer Institute) ;
  • Sinha, D. (Department of Environmental Carcinogenesis and Toxicology Chittaranjan National Cancer Institut) ;
  • Roy, M. (Department of Environmental Carcinogenesis and Toxicology Chittaranjan National Cancer Institut) ;
  • Bhattacharya, R.K. (Department of Environmental Carcinogenesis and Toxicology Chittaranjan National Cancer Institut) ;
  • Siddiqi, M. (Department of Environmental Carcinogenesis and Toxicology Chittaranjan National Cancer Institute)
  • Published : 2001.10.01

Abstract

Modulation of events characteristic of carcinogenesis or of cancer cells is being emphasized as a rational strategy to combat cancer. This is achieved through chemoprevention by a variety of agents. Phenolic compounds, particularly polyphenols, have been shown to be highly active in this regard. Certain cellular and molecular events relevant to carcinogenesis are modified by polyphenols. The present investigation has been carried out to examine some of these aspects.(omitted)

Keywords