Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2001.10a
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- Pages.35-36
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- 2001
NOVEL LEAD STRUCTURES AND MECHANISMS FOR CANCER CHEMOPREVENTION
- Gerhauser, C. (Deutsches Krebsforschungszentrum (DKFZ), Toxikologie und Krebsrisikofaktoren (C0202 Chemopravention))
- Published : 2001.10.01
Abstract
Nutrition influences cancer incidence and offers a variety of preventive dietary factors including non-nutritive plant metabolites. To identify novel potential chemopreventive agents, we have set up cell- and enzyme-based in vitro marker systems relevant for prevention of carcinogenesis in vivo. This experimental approach led to the identification of Xanthohumol (Xn), a prenylated chalcone from hop (Humulus lupulus L.) as a most promising broad-spectrum chemopreventive agent.(omitted)
Keywords