Effects of Methyltestosterone and Flutanide on Phospholipid Hydroperoxide Glutathione Peroxidase Gene Expression in the Reproductive System of Male Mice

  • Kang, Min-Joung (College of Veterinary Medicine, Chungbuk National University) ;
  • Nam, Sang-Yoon (College of Veterinary Medicine, Chungbuk National University) ;
  • Kwon, Young-Bang (College of Veterinary Medicine, Chungbuk National University) ;
  • Kang, Jong-Koo (College of Veterinary Medicine, Chungbuk National University)
  • 발행 : 2001.05.01

초록

Phospholipid hydroperoxide glutathione peroxidase (PHGPx) is an antioxidant selenoenzyme which interacts directly with and diminishes peroxidized phospholipids, cholesterol and cholesteryl ester in tissues. PHGPx activity appears in most tissues, but is especially high in testis. In testis, PHGPx level decreases in hypophysectomized rats but is partially restored after gonadotropin treament.(omitted)

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