한국독성학회:학술대회논문집 (Proceedings of the Korean Society of Toxicology Conference)

한국독성학회 (Korean Society of Toxicology & Korea Environmental Mutagen Society)
권호 표지

EFFECTS OF SUBCHRONIC PATERNAL EXPOSURE TO CYCLOPHOSPHAMIDE AND ACROLEIN ON MALE FERTILITY AND EARLY EMBRYONIC DEVELOPMENT IN RATS

  • Oran-Kwon (Department of Toxicology, National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Kwack, Seung-Jun (Department of Toxicology, National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Shin, Jae-Ho (Department of Toxicology, National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Kim, Soon-Sun (Department of Toxicology, National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Sohn, Kyung-Hee (Department of Toxicology, National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Kim, So-Hee (Department of Toxicology, National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Lee, Rhee-Da (Department of Toxicology, National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Kim, Byung-Ho (Department of Toxicology, National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Park, Chul-Hoon (Department of Toxicology, National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Ha, Won-Kwang (Department of Toxicology, National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Park, Kui-Lea (Department of Toxicology, National Institute of Toxicological Research, Korea Food and Drug Administration)
  • 발행 : 2001.05.01
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초록

The purpose of the present studies was to investigate the effects of subchronic paternal treatment of cyclophosphamide (CP) and acrolein on male fertility and early embryonic development. Two approaches were pursued. The first was to perform in vivo test for observing the adverse effects of CP and acrolein on the function og male reproductive system and pregnancy outcome.(omitted)

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