Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2001.05a
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- Pages.128-128
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- 2001
PRECLINICAL TOXICITY STUDY OF A NEW PHOSPHODIESTERASE-5 INHIBITOR (II) FOUR-WEEK SUBACUTE TOXICITY STUDY IN RATS
- Hyeon Cho (Research Laboratories, Dong-A Pharm. Co., Ltd.) ;
- Kim, Dong-Hwan (Research Laboratories, Dong-A Pharm. Co., Ltd.) ;
- Kang, Kyung-Koo (Research Laboratories, Dong-A Pharm. Co., Ltd.) ;
-
Ahn, Byoung-Ok
(Research Laboratories, Dong-A Pharm. Co., Ltd.)
;
- Kim, Won-Bae (Research Laboratories, Dong-A Pharm. Co., Ltd.)
- Published : 2001.05.01
Abstract
Toxic effects of a new phosphodiesterse-5 inhibitor, DA-8159, were investigated in Sprague-Dawley rats by repeated oral administration. Four groups of 10 male and 10 female rats were treated with DA-8159 at a dose of 0, 40, 80, or 320 mg/kg/day for 4 weeks.(omitted)
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