Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)

Korean Society of Toxicology & Korea Environmental Mutagen Society (한국독성학회)
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COMBINED IN VITRO ASSAY FOR 3T3 NRU PT ASSAY AND PHOTOHEMOLYSIS AS PART OF PHOTOTOXICITY TEST

  • Chunja Nam (Skin Research Institute, Pacific R＆D Center) ;
  • Kim, Baehwan (Skin Research Institute, Pacific R＆D Center) ;
  • Lee, Byoungseok (Skin Research Institute, Pacific R＆D Center) ;
  • Seongjoon Moon (Skin Research Institute, Pacific R＆D Center) ;
  • Ihseop Chang (Skin Research Institute, Pacific R＆D Center)
  • Published : 2001.05.01
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Abstract

The aim of this study was to assess a possible alternative method as replacement for in vivo phototoxicity test. The 3T3 mouse fibroblast neutral red uptake phototoxicity assay (3T3 NRU PT assay) is a screening method for studying DNA or cellular damage. Photohemolysis assay is a mechanistic study for investigating oxygen-dependent membrane damage.(omitted)

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