Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2001.05a
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- Pages.114-114
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- 2001
Effect of di-n-butyl-phthalate on cytotoxic activity of natural killer cells in C57BL/6
- Juno H. Eom (Department of Toxicology, National Institute of Toxicological Research, Korea Food and Drug Administration) ;
- Chung, Seung-Tae (Department of Toxicology, National Institute of Toxicological Research, Korea Food and Drug Administration) ;
-
Kim, Jin-Ho
(Department of Toxicology, National Institute of Toxicological Research, Korea Food and Drug Administration)
;
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Park, Jae-Hyun
(Department of Toxicology, National Institute of Toxicological Research, Korea Food and Drug Administration)
;
- Chung, Hyung-Jin (Department of Toxicology, National Institute of Toxicological Research, Korea Food and Drug Administration) ;
- Hwang, In-Chang (Department of Toxicology, National Institute of Toxicological Research, Korea Food and Drug Administration) ;
- Kim, Dong-Sup (Department of Toxicology, National Institute of Toxicological Research, Korea Food and Drug Administration) ;
- Kim, Hyung-Soo (Department of Toxicology, National Institute of Toxicological Research, Korea Food and Drug Administration)
- Published : 2001.05.01
Abstract
Di-n-butyl phthalate (DBP) is not only a plasticizer and solvent used in industry but also one of endocrine disruptor chemicals, a low level contaminant found in a wide variety of different media ranging from drinking water to infant formulae. To evaluate the cytotoxic function of NK cells in mice after contact with DBP, C57BL/6 female mice were orally dosed with di-n-butyl phthalate (250, 500, or 750 mg/kg body weight) for 14 consecutive days, and the control mice were administered vehicle (corn oil).(omitted)
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