THE ESSENTIAL ROLE OF PI3-KINASE IN THE INDUCTION OF GLUTATHIONE S-TRANSFERASE BY TERT-BUTYLHYDROQUINONE AND OLTIPRAZ: DIFFERENTIAL EFFECTS ON Nrf2/ARE ACTIVATION

  • 발행 : 2001.05.01

초록

The phase II detoxifying enzymes are inducible by a variety of compounds and play an essential role for the protection of cells. Many of chemoprotective agents trigger cellular signals for the phase II enzyme induction, which subsequently activate gene transcription through ARE activation.(omitted)

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