한국독성학회:학술대회논문집 (Proceedings of the Korean Society of Toxicology Conference)
- 한국독성학회 2001년도 International Symposium on Signal transduction in Toxicology
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- Pages.84-88
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- 2001
Thioredoxin System and Redox Signaling; Defence against Stress and Toxicity
- Yodoi, Junji (Institute for Virus Research, Kyoto University) ;
- Masutani, Hiroshi (Institute for Virus Research, Kyoto University) ;
- Nakamura, Hajime (Institute for Virus Research, Kyoto University)
- 발행 : 2001.05.01
초록
Human Thioredoxin (TRX) with with redox-active dithiol (C-C-Y-C-) in the active site has been cloned as adult T cell leukemia derived factor produced by HTLV-I transformed cells. Thioredoxin (TRX) is one of the major components of the thiol-reducing system and plays multiple roles in cellular processes such as proliferation, apoptosis and gene expression.(omitted)
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