한국독성학회:학술대회논문집 (Proceedings of the Korean Society of Toxicology Conference)

한국독성학회 (Korean Society of Toxicology & Korea Environmental Mutagen Society)
권호 표지

TPA-and $H_2O_2$- induced Apoptosis by Epigenetic Mechanism and Preventive Effect of L-Carnosine on TPA- and $H_2O_2$- induced Apoptosis of v-myc Transformed Rat Liver Epithelial Cells

  • Kang, Kyung-Sun (Department of Veterinary Public Health, Laboratory of Environmental Health, College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University) ;
  • Yun, Jun-Won (Department of Veterinary Public Health, Laboratory of Environmental Health, College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University) ;
  • Cho, Sung-Dae (Department of Veterinary Public Health, Laboratory of Environmental Health, College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University) ;
  • Lee, Yong-Soon (Department of Veterinary Public Health, Laboratory of Environmental Health, College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University)
  • 발행 : 2001.05.01
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초록

Apoptosis is characterized by DNA fragmentation, chromatin condensation and plasma membrane blebbing. These apoptotic processes have been mainly associated with genetic mechanisms. Recently, these processes have been also associated with mitochondrial events that include the release of cytochrome c and Diablo/SMAC by modulation of mitochondrial membrane permeability.(omitted)

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