한국독성학회:학술대회논문집 (Proceedings of the Korean Society of Toxicology Conference)
- 한국독성학회 2001년도 International Symposium on Signal transduction in Toxicology
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- Pages.1-8
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- 2001
PROSTAGLANDINS AND THE REGULATION OF TUMOUR CELL GROWTH
- Bailey, David-Bishop (Department of Cardiac, Vascular & Inflammation Research, William Harvey Research Institute, Charterhouse Square, Queen Mary′s University) ;
- Jane A. Mitchell (Unit of Critical Care Medicine, Royal Brompton Hospital)
- 발행 : 2001.05.01
초록
Increased expression of inducible cyclo-oxygenase (COX-2) is associated with a wide variety of tumours. In addition inhibitors of COX have shown a great deal of promise in vitro and in animal models as potential anti-tumour therapies. COX enzymes utilise the substrate arachidonic acid to produce prostaglandin (PO)H
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