Application of Transfer Insensitive Labeling Technique (TILT) in Ischemic Cerebrovascular Diseases

  • 이승구 (연세대학교 의과대학 진단방사선과학교실) ;
  • 김동익 (연세대학교 의과대학 진단방사선과학교실) ;
  • 김상흠 (연세대학교 의과대학 진단방사선과학교실) ;
  • 김시연 (연세대학교 의과대학 진단방사선과학교실) ;
  • 인연권 (연세대학교 의과대학 진단방사선과학교실)
  • Published : 2001.11.01

Abstract

Purpose: To assess the clinical usefulness of Transfer Insensitive Labeling Technique (TILT) in t evaluation of ischemic cerebrovascular disease. Method: Arterial spin labeling (ASL) is a method of perfusion weighted imaging usin endogenous water as a tracer. To avoid MT-related artifacts, which is common in usual A technique, a transfer insensitive labeling technique (TILT) was used, which globall manipulate macromolecular spins in the same way by both labeling and reference preparatio while free water is labeled in one case and left unchanged in the other. Philips Interal 1.5 T system was used. 40cm FOV and 32 repeated measurements were done because of the wea perfusion signal. 5 slices of supratentorial brain were obtained in 5 patients {MCA infar (n=3), moyamoya disease (n=2)}. We simultaneously obtained contrast enhanced T2*-weighted perfusion MRI and correlate to TILT images.

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