대한치과보존학회:학술대회논문집 (Proceedings of the KACD Conference)
- 대한치과보존학회 2001년도 추계학술대회(제116회) 및 13회 Workshop 제3회 한ㆍ일 치과보존학회 공동학술대회 초록집
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- Pages.566.2-566
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- 2001
The effect of taurine and alendronate on the osteoclast differentiated by the sonicated extracts of Porphyromonas Gingivalis in vitro
- Kim, Hyung-Su (Department of Conservative Dentistry, Yonsei University) ;
-
Lee, Seung-Jong
(Department of Conservative Dentistry, Yonsei University)
;
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Lee, Chan-Young
(Department of Conservative Dentistry, Yonsei University)
;
-
Kum, Kee-Yeon
(Department of Conservative Dentistry, Yonsei University)
- 발행 : 2001.11.01
초록
The objective of this study was to investigate the ability of alendronate and taurine in inhibiting in vitro osteoclast differentiation induced by bacteria. Whole cell sonicates of P. gingivalis were used as an osteoclast-stimulating factor in a mouse coculture system and differentiated osteoclasts were confirmed by tartrate-resistant acid phosphatase (TRAP) staining. Alendronate at the concentrations of 10-7, 10-6, and 10-5 M, and taurine at the concentrations of 4mM, 8mM, and 12mM were used.(omitted)
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