The Anti-inflammatory, Analgesic and Antipyretic Actions of Loxoprofen Sodium in Intramuscular Administration in Rats and Mice

Loxoprofen Sodium의 근육투여시 소염, 진통 및 해열작용

Loxoprofen sodium is an orally used anti-inflammatory, analgesic and antipyretic agent. For alleviation or inhibition of the pain symptoms regardless of referred or superficial pain, the prompt absorption of a drug and its immediate bioavailability might be generally required for a formulation or development of a new drug. Therefore, in intramuscular administration, its anti-inflammatory, analgesic, and antipyretic effects were evaluated compared with an oral administration in animals. The occurrence of gastric damages which is common in nonsteroidal anti-inflammatory drugs was also observed.