Discovery of New Proteinase Inhibitor for the Treatment of Osteoporosis

  • 발행 : 2001.04.01

초록

■ Cathepsin K is a attractive target for selectively and efficiently modulating the osteoclastic bone resorption. ■ OST-1857 is a lead compound which is specifically targeted to cathepsin K and showed efficacy in TPTX rats. ■ OST-compounds are in process of the preclinical study, joined by Yuhan research center.

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