한국식품영양과학회:학술대회논문집 (Proceedings of the Korean Society of Food Science and Nutrition Conference)
- 한국식품영양과학회 2001년도 International Symposium on Food,Nutrition and Health for 21st Century
- /
- Pages.61-68
- /
- 2001
ANIMAL AND HUMAN STUDIES ON THE ROLE OF SOYBEAN, RICE AND NUTS CONSUMPTION IN HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS
- Imaizumi Katsumi (Laboratory of Nutrition Chemistry, Graduate School of Agriculture, Kyushu University)
- 발행 : 2001.12.01
초록
Soybean, rice and nuts are the staple foods in South East Asia. In order to clarify the function of these foods in relation to coronary heart diseases, we have done a series of experiments using animals and humans. Soybean protein preparations (SPI) in comparison with an animal protein, casein (CAS), resulted in reducing atherosclerotic lesion development in apolipoprotein (apo) E deficient mice that develop an advanced lesion similar to that in humans. This action was attributed to the protein, since the ethanol-extracted SPI (EE-SPI), from which isoflavones and saponins removed, lowered the lesion development in apo E-deficient mice. However, The EE-SPI, compared to the SPI, resulted in a decrease of mRNA for key proteins of cholesterol metabolism (low density lipoprotein receptor and cholesterol 7
키워드