Enzymatic synthesis of ester-linked conjugates of amino acid and monosaccharide

  • 전규종 (한국과학기술원 화학공학과) ;
  • 박오진 (한국과학기술원 화학공학과) ;
  • 신문식 (한국과학기술원 화학공학과) ;
  • 양지원 (한국과학기술원 화학공학과)
  • Published : 2000.11.09

Abstract

In this study the enzymatic synthesis of ester-linked conjugates of amino acid and monosaccharide in pyridine was tested by the catalysis of Optimase M-440, an alkaline serine pretense. Optimase M-440 showed the higher activity in the reaction of monosaccharides which have one or more primary -OH groups. And also Optimase M-440 showed high regioselectivity; The transesterification of primary -OH group selectively occurred.

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