The Radioprotective Effects of Bu-Zhong-Yi-Qi-Tang as a Prescriptions of Traditional Chinese Medicine in Irradiated Mice

  • Kim, Sung-Ho (Department of Anatomy, College of Veterinary Medicine, Chonnam National University) ;
  • Kim, Se-Ra (Department of Anatomy, College of Veterinary Medicine, Chonnam National University) ;
  • Heon Oh (Department of Anatomy, College of Veterinary Medicine, Chonnam National University) ;
  • Yang, Jung-Ah (Department of Anatomy, College of Veterinary Medicine, Chonnam National University) ;
  • Jo, Sung-Kee (Food Irradiation Team, Korea Atomic Energy Research Institut) ;
  • Byun, Myung-Woo (Food Irradiation Team, Korea Atomic Energy Research Institut) ;
  • Yee, Sung-Tae (Department of Biology, Sunchon National University)
  • Published : 2000.09.01

Abstract

We performed this study to determine the effect of Bu-Zhong-Yi-Qi-Tang, as a prescription of traditional Oriental medicine, and its major ingredients on jejunal crypt survival, endogenous spleen colony formation, and apoptosis in jejunal crypt cells of mice irradiated with high and low dose of r-radiation. Bu-Zhong-Yi-Qi-Tang administration before irradiation protected the jejunal crypts (p<0.0001), increased the formation of endogenous spleen colony (p<0.05) and reduced the frequency of radiation-induced apoptosis (p<0.05). (omitted)

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